WikiMSK:Updates

Latest RCTs

Could the Hanging Drop Technique Be an Alternative Method to Loss of Resistance in Cervical Epidural Injections?: CONCLUSIONS: The LOR technique was superior to the HD for cervical ILESIs. More studies with larger sample sizes may provide more precise and detailed information.; Hamit Goksu. Pain physician. 2025-06-04 00:00:00
Safety and Efficacy of Platelet-Rich Plasma versus Genicular Nerve Radiofrequency Ablation in Knee Osteoarthritis: An Open-Label, Prospective, Randomized, Clinical Trial: CONCLUSION: For patients with chronic knee osteoarthritis, intraarticular platelet-rich plasma therapy may offer superior sustained pain relief and a lower disability index compared to conventional...; Annu Navani. Pain physician. 2025-06-04 00:00:00
Short-Term Effects of Kinesio Taping on Pain and Functionality in Patients With Cervical Spine Surgery: CONCLUSION: Integrating KT into a CR programme during the early postoperative phase of cervical spine surgery may improve clinical outcomes, specifically in pain intensity, PPT, disability levels a...; Zafer O Toktaş. European journal of pain (London, England). 2025-05-29 00:00:00
Impact of Intermittent Theta Burst Stimulation on Pain Relief and Brain Connectivity in Chronic Low Back Pain: CONCLUSION: iTBS may alleviate pain in CLBP patients by enhancing DLPFC connectivity with the cerebellum and occipital gyrus.; Chuhuai Wang. European journal of pain (London, England). 2025-05-05 00:00:00
HOPE for Hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorder (HSD)-A Pilot Randomised Controlled Trial of Feasibility, Acceptability and Appropriateness: CONCLUSION: The HOPE program seemed feasible, acceptable and appropriate, with preliminary improvements in worst pain intensity and impact of hypermobility. Our findings warrant a fully powered tri...; Cliffton Chan. European journal of pain (London, England). 2025-04-29 00:00:00
Manual therapy and neck-specific exercise are equally effective for treating non-specific neck pain but only when exercise adherence is maximised: A randomised controlled trial: CONCLUSION: A four-week intervention of manual therapy was more effective than exercise, however when exercise adherence was ≥95 %, the interventions were equally effective. Manual therapy may on...; Ion Lascurain-Aguirrebeña. Musculoskeletal science & practice. 2025-04-24 00:00:00
The Effect of Information on the Time Course of Pain During an Episode of Acute Experimentally Induced Low Back Pain-A Randomised Experiment: CONCLUSIONS: We simulated an episode of low back pain and found that information based on tissue sensitivity and advice to remain active did not improve pain compared to information referencing tis...; T Skuli Palsson. European journal of pain (London, England). 2025-04-20 00:00:00
Stair climb muscle power is associated with gait speed, sit-to-stand performance, patient-reported outcomes and objective measures of mechanical muscle function in individuals with knee osteoarthri...: CONCLUSIONS: SCT power correlates positively with functional performance, PROMs and mechanical lower limb muscle function in male and female individuals with knee-OA.; S Peter Magnusson. Musculoskeletal science & practice. 2025-04-18 00:00:00
Cryo-Induced Hypoalgesia: The Effects of an Acute Cryochamber Exposure on Pain Perception-A Randomised Controlled Cross-Over Trial: CONCLUSIONS: This study demonstrates that a three-minute cryochamber exposure induces robust hypoalgesia in healthy participants, as indicated by increased PPT, lasting up to 30 min but gradually d...; Thomas Hilberg. European journal of pain (London, England). 2025-04-05 00:00:00
Greater Occipital Nerve Block at Two Levels Spares the Need for an Epidural Blood Patch for Managing Postdural Puncture Headache: A Randomized Comparative Trial: CONCLUSION: Bilevel GONB provided was superior to single level blocks and intramuscular injection with no 24 hour postprocedure failure, a low recurrence rate, and totally negated the need for an e...; Samar A Salman. Pain physician. 2025-04-01 00:00:00
Evaluation of Genicular Nerve Blocks Durations With and Without Corticosteroid: A Single-blind, Randomized Controlled Trial: CONCLUSION: The addition of a corticosteroid to local anesthetic for GNB may prolong initial analgesic effects within the first postprocedure 24 hours. However, there is no analgesic difference in ...; Chong H Kim. Pain physician. 2025-04-01 00:00:00
Ultrasound-Guided Stellate Ganglion Block for the Treatment of Chronic Migraine in Adults: Study Protocol for a Randomized, Open-Label, Blinded Endpoint Trial: CONCLUSIONS: This study is a randomized controlled trial with a relatively large sample size to demonstrate the potential benefits of combined SGBs and drug therapy for CM patients. In the short te...; Fang Luo. Pain physician. 2025-04-01 00:00:00
Rivaroxaban versus enoxaparin as thromboprophylaxis in degenerative spine surgery: a randomized blinded non-inferiority study: CONCLUSION: This study shows that rivaroxaban effectively prevents VTE incidence in degenerative disc spinal surgeries which is non-inferior to enoxaparin in terms of VTE prophylaxis. Furthermore, ...; Hadi Esmaily. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-03-31 00:00:00
Effect of a Surgeon-Directed Cocktail of Ropivacaine, Methylprednisolone, and Ketoprofen on Postoperative Pain and Ambulation in Adolescent Idiopathic Scoliosis Surgery: A Double-Blind Randomized C...: CONCLUSIONS: Surgeon-directed cocktail therapy alone is insufficient to achieve significant improvements in pain control, as evidenced by the minimal impact on NRS scores and early ambulation promo...; Yukihiro Matsuyama. Spine. 2025-03-28 00:00:00
The influence of education on pain during and following acute exercise in people with knee osteoarthritis: A randomised controlled trial: CONCLUSION: A single exercise session reduces pain in people with knee OA, but this was not influenced by pre-exercise education about EIH. Further research is needed to understand if and how EIH c...; Matthew D Jones. Musculoskeletal science & practice. 2025-03-26 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. RCTs from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

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Latest Systematic Reviews

Machine learning-based models for outcome prediction in skull base and spinal chordomas: a systematic review and meta-analysis: CONCLUSION: Our results indicated that ML models demonstrated robust predictive performance across various outcomes in chordomas, with pooled C-index, AUC, and ACC values ranging from 0.80 to 0.86 ...; Mohammad Amin Habibi. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-06-14 00:00:00
Risk Factors for Postoperative Coronal Malalignment in Degenerative Lumbar Scoliosis and Its Impact on Clinical Outcomes: A Systematic Review and Meta-Analysis: CONCLUSION: Female sex, more severe preoperative coronal deformity, and insufficient correction of the lumbosacral curve are significant factors for postoperative CM following DLS surgery. The pres...; Shibao Lu. Spine. 2025-06-13 00:00:00
Risk factors for facet joint violation in minimally invasive and open lumbar interbody fusion: a systematic review and meta-analysis: CONCLUSION: BMI ≥ 30, screw placement at L5, and a lower PSA increase the risk of FJV during lumbar interbody fusion. Screw placement at L4 and the use of 3D navigation in MISS are associated wit...; Grzegorz Miękisiak. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-06-09 00:00:00
The effect of symptom duration on the outcomes of lumbar discectomy for radicular pain secondary to lumbar disc herniation: a systematic review and meta-analysis: CONCLUSIONS: There is low quality evidence suggesting that discectomy within 12 months of symptom onset can improve postoperative leg pain. There was no significant effect of symptom duration on po...; Hasan Raza Mohammad. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-06-09 00:00:00
Answer to the Letter to the Editor of Z. Guo, et al. concerning "Pulmonary function does not improve after 10 years of posterior spinal fusion in adolescent idiopathic scoliosis: a systematic revi...: No abstract; Gonzalo Mariscal Ruiz-Rico. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-06-05 00:00:00
A Systematic Review of Self-Reported Pain Rating Scales for Children and Adolescents: CONCLUSIONS: Self-report pain scales that include visual aids such as colors and facial features may allow for the better assessment of pediatric pain than do pain scales without visual aids; howev...; Shuhan He. Pain physician. 2025-06-04 00:00:00
Letter to the editor concerning "pulmonary function does not improve after 10 years of posterior spinal fusion in adolescent idiopathic scoliosis: a systematic review and meta-analysis" by Burgos, ...: No abstract; Nan Ning. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-05-31 00:00:00
Support or constraint? A comprehensive analysis of postoperative cervical bracing practices: insights from the Italian society of neurosurgery (SINch) survey and a systematic review of the literature: CONCLUSIONS: Cervical bracing following single- or double-level ACDF without plating remains controversial, with no significant difference in fusion rates, kyphosis progression, or cage migration b...; Andrea Fanti. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-05-30 00:00:00
Answer to the letter to the editor of B. Wang, et al. concerning "Impact of erector spinae plane block on postoperative recovery quality in spinal surgery: a systematic review and meta-analysis" by...: No abstract; Ying Xie. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-05-28 00:00:00
Adverse Impact of Obesity on Lumbar Spine Fusion, Patient-Reported Outcomes and Costs: A Systematic Review and Meta-Analysis: CONCLUSION: This meta-analysis suggests that obesity is significantly associated with higher nonunion rates, poorer patient-reported outcome measures including Oswestry Disability Index, Visual Ana...; Michael P Steinmetz. Spine. 2025-05-28 00:00:00
The Impact of Transcranial Magnetic Stimulation (TMS) on Depressive Symptomatology in Patients with Chronic Pain Disorders: A Systematic Review: CONCLUSIONS: The impact of TMS on depressive symptomatology among patients with chronic pain is a complex subject. Considering the diversity of the protocols and results encountered, future researc...; Patrick Alexandre Alves. Pain medicine (Malden, Mass.). 2025-05-27 00:00:00
Computed tomography versus magnetic resonance imaging of the cervical spine in the spinal clearance of trauma patients: a systematic review and meta-analyses: CONCLUSION: Trauma patients with a negative CT cervical spine had a 17% chance of missed injuries if MRI cervical spine was not performed, with paediatric and alert patients having a higher risk. T...; Hwee Weng Dennis Hey. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2025-05-23 00:00:00
Effectiveness and reporting quality of blood flow restriction training in the rehabilitation of patients with upper limb musculoskeletal disorders: A systematic review: CONCLUSIONS: This systematic review identified limited and low-quality evidence that BFRT is effective in the physical rehabilitation of patients with upper limb musculoskeletal disorders. Addition...; Filip Struyf. PM & R : the journal of injury, function, and rehabilitation. 2025-05-23 00:00:00
Family-Related Factors in Children and Adolescents With Chronic Pain: A Systematic Review: CONCLUSIONS: Most of the studies were cross-sectional with a moderate or high risk of bias, reporting on the parenting individual-, dyadic-, and contextual-related factors. In the included studies,...; Jordi Miró. European journal of pain (London, England). 2025-05-23 00:00:00
Normative Thoracic, Lumbar, Pelvic and Global Sagittal Alignment Parameters for Asymptomatic Adults: A Systematic Review and Meta-Analysis of >35,900 Volunteers: CONCLUSION: LL-S1, PI and PT were all higher in women. Regional TK, PT, PI-LL, SVA, TPA all increased with age, while LL-S1 and SSA decreased. Global TK, regional TK, LL-S1, PI, and PI-LL all had s...; Zeeshan M Sardar. Spine. 2025-05-23 00:00:00

If anyone is good at writing pubmed searches then please help out with improving this section. Reviews from: Pain, Pain physician, Pain Medicine, European journal of pain, Musculoskeletal science practice, American journal of PM & R, PM & R, Spine, European spine journal, The spine journal

Pubmed Link